| Info. | Vol.11 - No.2 (2017.06.20) |
|---|---|
| Title | Flexible and Implantable Capacitive Microelectrode for Bio-potential Acquisition |
| Authors | Seung Min Lee1,??/sup>, Hang Jin Byeon2,??/sup>, Bong Hoon Kim3, Jungyup Lee3, Ji Yoon Jeong3, Joong Hoon Lee4, Jin-Hee Moon5, Cheolsoo Park6, Hyuk Choi7,*, Sang-Hoon Lee4 & Kwang-Ho Lee8,* |
| Institutions | 1School of Electrical Engineering, College of Creative Engineering, Kookmin University, Seoul 02707, Republic of Korea 2Sensor Solution Lab, Material & Production Research Institute, LG Electronics, Woomyun R&D Campus, Seoul 06755, Republic of Korea 3Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA 4Department of Biomedical Engineering, College of Health Science, Korea University, Seoul 02841, Republic of Korea 5Department of Research & Development of Medical Device Development Center in Osong Medical Innovation Foundation, Cheongju 28160, Republic of Korea 6Department of Computer Engineering, Kwangwoon University, Seoul 01897, Republic of Korea 7Department of Medical Science, Graduate School of Medicine, Korea University, Seoul 02841, Republic of Korea 8Department of Advanced Material Science and Engineering, College of Engineering, Kangwon National University, Chuncheon 25561, Republic of Korea ??/sup>These authors contributed equally to this work. *Correspondence and requests for materials should be addressed to H. Choi (hyuk76@korea.ac.kr) and K-H. Lee (khmhlee@kangwon.ac.kr) |
| Abstract | Electrodes should be adhered onto the body steadily under motion, and implanted stably into the tissue without any damages while maintaining conformal contact. Although most electrodes are fabricated with biocompatible materials, they should be shielded from tissues to prevent mechanical delamination from the device itself and to avoid adverse effects such as irritation, allergic reactions, or inflammation. Herein, we demonstrate a simple process for the development of a flexible and implantable capacitive electrode based on a minimal incision accessible design with polyimide (PI) and Gold/Titanium (Au/Ti) layers and completely encapsulated in a polydimethylsiloxane (PDMS) substrate. Electrodes of three different sizes (recording site diameters of 1.8 mm, 2.8 mm, and 3.8 mm, respectively) were fabricated and examined in this work. Electrocardiography (ECG) was recorded in the dorsal area of the rat for 4 weeks for biological signal checkup. We obtained stable and robust ECG signals owing to the intrinsic property of capacitive coupling, with almost no leakage current compared to the direct contact electrode for the applied current over the range of 0 to 10 mA. These results indicate that our electrode can be used to detect bio-signals effectively in the long term, and can play a role in electroceuticals in the near future. |
| Keyword | Electrode: Polydimethylsiloxane (PDMS), Gold/Titanium (Au/Ti), Electrocardiography (ECG), Capacitive Coupling, Bio-potential |
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