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Info. Vol.3 - No.1 (2009.03.20)
Title Fabrication of Nanopattern by Nanoimprint Lithography for the Application to Protein Chip
Authors Ho-Gil Choi1, Dong-Sik Choi2, Eun-Wook Kim3, Gun-Young Jung3, Jeong-Woo Choi1,2 & Byung-Keun Oh1,2
Institutions 1Department of Chemical & Biomolecular Engineering and
2Interdisciplinary Program of Integrated Biotechnology, #1 Shinsudong, Mapo-gu, Sogang University, Seoul 121-741 Korea
3Department of Materials Science and Engineering, Gwangju Institue of Science and Technology (GIST), #1 Oryong-dong, Buk-gu, Gwangju 500-712, Korea
Correspondence and requests for materials should be addressed to B.K. Oh (bkoh@sogang.ac.kr)
Abstract Nanoimprint lithography is an efficient and versatile method for fabricating nanosize patterned devices on account of its superior resolution, reliability and process speed compared to conventional lithography. Using this technique, microscale to nanoscale structures, called nanopore structures, were fabricated over a large area on a gold (Au) surface under mild conditions, such as room temperature and low pressure. The fabricated nanopatterns were characterized by field emission scanning electron microscopy. A protein array was fabricated on the pore shaped patterns and characterized by fluorescence microscopy.The proposed patterning process of the protein on Au substrates can be applied as potentially usable elements in the development of biosensors and other bioelectronic devices.
Keyword Nanoimprint lithography, Nanopore shaped pattern, Protein array, Prostate specific antigen
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