| Info. | Vol.1 - No.1 (2007.03.20) |
|---|---|
| Title | Biotin-Streptavidin Binding Detection by Single-Wall Carbon Nanotube Network Junctions Fabricated with Surface Programmed Assembly Method |
| Authors | Byung Yang Lee1, Young Wook Kim2, Dong Joon Lee1 & Seunghun Hong1 |
| Institutions | 1School of Physics and Astronomy, Seoul National University, Seoul 151-747, Korea 2School of Electrical Engineering, Seoul National University, Seoul 151-747, Korea Correspondence and requests for materials should be addressed to S. Hong (shong@phya.snu.ac.kr) |
| Abstract | This paper presents the results of protein binding detection using single wall carbon nanotube network junctions as the transducer channel. The carbon nanotube junctions have been fabricated by using surface programmed assembly, where the carbon nanotubes align themselves and assemble in predefined patterns without using any external force or unconventional process like high temperature treatment,etc. This process leaves exposed the SiO2 surface on which the carbon nanotubes are assembled. This enables biotin immobilization by simple chemistry. When streptavidin is injected, the strong binding between biotin and streptavidin is detected by the carbon nanotube junction, yielding a highly sensitive streptavidin sensor for protein binding studies. |
| Keyword | Surface programmed assembly, Single walled carbon nanotube, Biotin, Streptavidin, Protein binding, Nanobiosensor |
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