| Info. | Vol.3 - No.3 (2009.09.20) |
|---|---|
| Title | Diagnostic Polymorphisms in the Mitochondrial DNA Allow Discrimination among Cervus elaphus Species |
| Authors | Hwan-Suck Chung1, Hye Jeong Lee1, Young Eun Kim2, Moonkyu Kang3, Seung Yong Hwang4, Ji-Hoon Kim4, Jin-Wook Jung4, In Hyuk Chung4, Min-Kyu Shin1,5, Moo-Chang Hong1, Yangseok Kim1 & Hyunsu Bae1 |
| Institutions | 1Department of Physiology, College of Oriental Medicine,
Kyung-Hee University, #1 Hoegi-dong, Dongdaemun-gu,
Seoul 130-701, Korea 2Purimed R & D Institute, Kyung-Hee University, #1 Hoegi-dong, Dongdaemun-gu, Seoul 130-701, Korea 3WhanIn Pharmaceutical Co., Ltd, Youngtong-gu, Suwon, Gyeonggi-do 443-370, Korea 4Department of Biochemistry, Hanyang University & GenoCheck Co. Ltd., Ansan, Gyeonggi-do 426-791, Korea 5BK21 Oriental Medical Science Center, Kyung-Hee University, Seoul 130-701, Korea Correspondence and requests for materials should be addressed to H. Bae (hbae@khu.ac.kr) |
| Abstract | Velvet antlers from Cervus elaphus species are one of most famous and commonly used medicinal materials in traditional oriental medicine. In this study, the variation in DNA sequences of the mitochondrial ATPase8 and cytochrome-c oxidase I (COI) genes of Cervus elaphus from China, the Republic of Altai, and Canada were evaluated. In addition, the sequence variation among Sika deer, Rein deer and Cervus elaphus species was also evaluated. Although the sequences of deer from the Republic of Altai and Canada were very similar, polymorphisms that were conserved in each species were observed in the ATPase8 and COI genes. Therefore, these polymorphic markers could be used to distinguish Cervus elaphus antlers from different locations. |
| Keyword | Cervus elaphus, Velvet antler, Deer, Polymorphisms, Mitochondrial DNA |
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