| Info. | Vol.6 - No.2 (2012.06.20) |
|---|---|
| Title | KOTIS: Korea Toxicogenomics Integrated System-The intelligent data warehouse for systems toxicology |
| Authors | Jin-Ho Yoo1, In-Cheol Ha1, Yunju Jo2, Ho-Sang Jeong3, Joon-Ik Ahn3 & Yangseok Kim2 |
| Institutions | 1ISTECH, Inc., Janghang-dong, Ilsandong-gu, Goyang, Gyeonggi-do,
Korea 2Department of Physiology, College of Oriental Medicine, Kyung Hee University, #1 Hoegi-dong, Dongdaemun-gu, Seoul, Korea 3Pharmacological Research Division, National Institute of Food and Drug Safety Evaluation, KFDA, Cheongwon-gun, Chungcheongbuk-do, Korea Correspondence and requests for materials should be addressed to Y.S. Kim (yskim1158@khu.ac.kr) |
| Abstract | KOTIS (Korea Toxicogenomics Integrated System) is the data warehouse for toxicogenomics research. It contains over 1,700 microarray experiments involved in 40 research projects. The main characteristic of KOTIS is that it has quality inspection modules for evaluating the quality of each microarray data. Furthermore, KOTIS automatically selects significant genes from the given experimental sets and provides well-annotated information with users. These powerful functions are very useful because users can easily identify the quality and the characteristics of each experiment without further data analysis. KOTIS is available at http://kotis.nifds.go.kr/. |
| Keyword | Toxicogenomics, Systems toxicology, Transcriptome data, Bioinformatics |
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