| Info. | Vol.10 - No.1 (2016.03.20) |
|---|---|
| Title | Paper-based Microfluidic Device for Bisphenol A Based Chemical Reaction and Image Analysis |
| Authors | Hyung-Geun Park1, Ja-Young Kim1 & Min-Kyeong Yeo1,* |
| Institutions | 1Department of Environmental Science and Environmental Research Center, College of Engineering, Kyung Hee University, 1732 Deogyeong-daero, Giheung-gu, Yongin-si, Gyeonggi-do 17104, Korea |
| Abstract | Bisphenol A (BPA) is a representative xenoestrogenic endocrine disruptor that is widely used in consumer products and remains in wastewater. A simple detection tool is urgently needed that can be used with the naked eye for environmental monitoring in situ. Therefore we studied modification methods of phenol and ferric reagents on a paper-based microfluidic device. The reaction between BPA and ferric reagent mixtures was examined using two types of ferric reagent mixtures (ferric chloride/ferricyanide and ferric nitrate/ferricyanide) at various ferric reagent mixture ratios (1 : 9, 3 : 7, 5 : 5, 7 : 3 and 9 : 1) and concentrations (BPA 100, 300, 500 and 1000 關g/mL and 1-5% ferric reagent mixtures). Verification of this paper-based microfluidic device was analyzed with a UV spectrophotometer. In addition, the changing color of the BPA reaction was demonstrated using histograms of the image statistics including the hue, saturation and value (HSV) analysis. Of the total BPA reactions, the optimal condition was identified as 1% ferric reagent mixture (5 : 5 ratio) and 5 關L of BPA loaded onto the paper-based microfluidic device. Moreover, the BPA detection abilities of ferric chloride/ferricyanide and ferric nitrate/ ferricyanide were similar to the changing images on the paper-based microfluidic device. The BPA paperbased microfluidic device is expected to be applied in situ and in factories as a low-cost, portable, simple and rapid detection system. |
| Keyword | Paper-based microfluidic device, Bisphenol A, Ferricyanide, Ferric chloride, Ferric nitrate |
| PDF File |
 # 2010년도 발행분 부터는 Springer 의 BioChip Journal 페이지에서 전문을 열람하실 수 있습니다.
# 학회회원 로그인 후 [ Springer BioChip Journal 열람하기 ] 버튼을 클릭하시면 새창으로 열립니다. |
