| Info. | Vol.3 - No.2 (2009.06.20) |
|---|---|
| Title | Enhancement of Biomolecular Mass Transport by Electrophoresis in Nanoscale Biosensors |
| Authors | Hyoki Kim1 & Sunghoon Kwon1 |
| Institutions | 1School of Electrical Engineering and Computer Science, Seoul National University, San 56-1, Shillim 9-dong, Gwanak-gu, Seoul 151-744, Korea Correspondence and requests for materials should be addressed to S. Kwon (skwon@snu.ac.kr ) |
| Abstract | We discuss the importance of active biomolecular transportation in nanoscale biosensors. Simulation results based on finite element method show the effect of electrostatic field driven by molecular transportation, and indicate that active driving force is necessary for efficient biomolecular detection in sample solution with low target concentration. Our numerical model provides a guideline to design nanoscale biosensors by considering various design parameters such as electric field intensity, molecular concentration, and sensor size. |
| Keyword | Mass transport, Nanoscale biosensor, Electrophoresis, FEM analysis, Microfluidics |
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