| Info. | Vol.12 - No.1 (2018.03.20) |
|---|---|
| Title | Paper-Based Biochip Assays and Recent Developments: A Review |
| Authors | Moonseong Park1, Byoung-Hoon Kang1 & Ki-Hun Jeong1,* |
| Institutions | 1Department of Bio and Brain Engineering and KAIST Institute for Optical Science and Technology, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea *Correspondence and requests for materials should be addressed to K.-H. Jeong (kjeong@kaist.ac.kr) |
| Abstract | Biomolecules in human body serve as biomarker for diagnosis of diseases, and paper-based biochips have become of much interest for development of biomolecule sensing. Cellulose micro-/nanofiber matrices consisting of paper allow not only capillary- driven flow without external pumping owing to abundant micro-/nanopores but also three-dimensional (3D) hierarchical micro-/nanostructures as 3D templates for microfluidic bioassays. Besides, colloidal and thermal evaporated metal nanoparticles on cellulose fibers offer huge opportunities in nanoplasmonic biosensing. Here, we review paper-based biochips including microfluidic paper-based assays and nanoplasmonic biosensors and further discuss micro-/nanofabrication of paper-based biochips and their applications in biomolecule detection. |
| Keyword | Paper, Biosensor, Biochip, Plasmonics, Nanofabrication |
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