| Info. | Vol.15 - No.4 (2021.12.20) |
|---|---|
| Title | Recent Developments in Surface Topography-Modulated Neurogenesis |
| Authors | Chaima Amri1, Tae-Hyung Kim2,* & Jin-Ho Lee1,3,* |
| Institutions | 1Department of Convergence Medical Sciences, School of Medicine, Pusan National University, Yangsan 50612, Korea 2School of Integrative Engineering, Chung-Ang University, Seoul 06974, Korea 3School of Biomedical Convergence Engineering, Pusan National University, Yangsan 50612, Korea |
| Abstract | "Repairing a nervous system damaged following an injury or as a consequence of neurodegeneration is still a challenging task. Yet, topography-based tissue engineering of neurons from different cell sources has demonstrated promising potential in the field. Substrate patterning through a range of methods including photolithography, nanofibers electrospinning, or microimprinting can not only impact the maturity of these vital neural cells but can also orient the differentiation of neural stem cells, a more prolific source of neurons. Furthermore, it has been shown that topography can guide the trans-differentiation of mesenchymal stem cells, a readily accessible cell source, towards a neuronal fate. Thus, in this review, we will cover the most recent methods used in topography-based neural tissue engineering." |
| Keyword | Tissue engineering, Topography, Neurons, Neural network, Stem cells, Trans-differentiation |
| PDF File |
 # 2010년도 발행분 부터는 Springer 의 BioChip Journal 페이지에서 전문을 열람하실 수 있습니다.
# 학회회원 로그인 후 [ Springer BioChip Journal 열람하기 ] 버튼을 클릭하시면 새창으로 열립니다. |
