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BioChip Journal

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Info. Vol.17 - No.2 (2023.06.20)
Title Microtubule WGM Sensor: Applications and Key Technologies
Authors Guoqing Yuan1,2,3, Hong Li 1,2,3*, Xinjian Luo 2, Lidan Lu 2, Lianqing Zhu 1,2,3
*Hong Li lihong@bistu.edu.cn
Institutions 1 Key Laboratory of the Ministry of Education for Optoelectronic Measurement Technology and Instrument , Beijing Information Science and Technology University, Beijing 100016, China
2 Beijing Laboratory of Optical Fiber Sensing and System, Beijing Information Science and Technology University Beijing100016, China
3Guangzhou Nansha Intelligent Photonic Sensing Research Institute,Beijing Information Science and Technology University ,Guangzhou 511462, China
Abstract Whispering gallery mode (WGM) microtubule resonators are widely used in highly sensitive sensing applications due to their ultra-high quality factor Q and extremely small mode size. Capillary microtubules, as sensing devices, have the advantages of
low reagent sample consumption, a large specifi c surface area to enhance analytical sensitivity, and a fast mass transfer rate to shorten analysis time. In recent years, research scholars have conducted extensive and in-depth studies on the optimization
of microtubule resonators. However, there are still several problems that limit the development of the technology applications and solutions that need to be explored. Therefore, this paper analyzes the current research status of resonant sensing
technology in microtubule whispering gallery, analyzes key problems, and points out research priorities and methods in coupled resonance technology and microtubule structure optimization. Finally, suggestions for future development are made.
Graphical Abstract
Capillary microcavity Whispering gallery mode (WGM) resonators with high Q and small mode volume are well suited for
applications in high sensitivity sensing. Such as biosensing, temperature sensing, pressure sensing, fl ow rate sensing, strain
sensing, and magnetic sensing, etc. The article analyzes the key technologies of capillary microcavity WGM resonant sens-
ing, focusing on the coupled resonant technology to excite capillary WGM, capillary structure parameter optimization and
sensor packaging, and provides an outlook on the future development.
Keyword Whispering gallery mode, Microtubule. Coupled resonance, Structural optimization , , Sensing technology
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