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(사)한국바이오칩학회 The Korean BioChip Society



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BioChip Journal

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Info. Vol.3 - No.1 (2009.03.20)
Title DVD Pick-up Based Optical Detection for Diffusive Mixing in Microchannels
Authors Seung-Yop Lee1,2, Vit Yim1, Jaehyun Kim1 & Jungyul Park1,2
Institutions 1Department of Mechanical Engineering, Sogang University, Sinsu-dong, Mapo-gu, Seoul 121-742, Korea
2Interdisciplinary Program of Integrated Biotechnology, Sogang University, Sinsu-dong, Mapo-gu, Seoul 121-742, Korea
Correspondence and requests for materials should be addressed to J. Park (sortpark@sogang.ac.kr)
Abstract Microfluidics deals with behavior, precise control, and manipulation of fluids at a micro scale. It has become increasingly prevalent in various applications, such as biomedical applications, inkjet heads, fuel cells, etc. The issue of mixing in microfluidic channels is often crucial in design, fabrication, and detection of microfluidic devices. In this paper, we propose a new optical method to characterize diffusive mixing in two types of microchannels (Y-type microchannel and premixer gradient generator). In order to measure the mixing of fluidic streams, we use an optical method using a DVD pick-up module, which is widely employed in optical storage systems installed within PCs or laptops. By injecting fluorescent dye into a solution, we measure the fluorescent intensities across the microchannels in order to visualize and quantify diffusive mixing. Experimental micrographs are compared with computational fluid dynamics (CFD) simulations. We show that our proposed optical scanner can be used as an alternative measurement system with high performance and cost-effectiveness in comparison with conventional optical tools such as epifluorescent microscopes and confocal microscopes.
Keyword Microfluidics, Optical pick-up, Optical scanner, Microchannel, Diffusive mixing
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