| Info. | Vol.16 - No.2 (2022.06.20) |
|---|---|
| Title | Recent Trends in Biosensors Based on Electrochemical and Optical Techniques for Cyanobacterial Neurotoxin Detection |
| Authors | Jeong Ah Park1, Yoseph Seo1, Hiesang Sohn1, Chulhwan Park1, Junhong Min2, Taek Lee1
*Junhong Min junmin@cau.ac.kr *Taek Lee tlee@kw.ac.kr |
| Institutions | 1 Department of Chemical Engineering, Kwangwoon University, Wolgye-dong, Nowon-gu, Seoul 01899, Republic of Korea 2 School of Integrative Engineering, Chung-Ang University, Heukseok-dong, Dongjak-gu, Seoul 06910, Republic of Korea |
| Abstract | Cyanobacteria that cause algal blooms are distributed worldwide and have been reported for a long time. Further, cyanobacterial growth is increasingly spreading because of anthropogenic eutrophication; this results in increasing damages by the production of a neurotoxin called cyanotoxin. Neurotoxins have adverse effects in humans, including disrupting signal transmission between neurons and muscles in various ways resulting in paralysis and death within minutes. To detect neurotoxins, analytical techniques such as high-performance liquid chromatography (HPLC), liquid chromatography–mass spectrometry (LC–MS), and enzyme-linked immunosorbent assay (ELISA) are being implemented, but have limitations as they are difficult to measure quickly in the field and are difficult to miniaturize. Introduction of biosensors for toxin detection provides a new direction as applying bioreceptors such as aptamers, antibodies, and nanomaterials can be used to create various sensors, without the limitations of conventional detection methods. In this review, we discuss the continued development of neurotoxin biosensors that are based on electrochemistry and optics. |
| Keyword | Cyanobacterial neurotoxin · Electrochemical · Optical · Biosensor |
| PDF File |
 # 2010년도 발행분 부터는 Springer 의 BioChip Journal 페이지에서 전문을 열람하실 수 있습니다.
# 학회회원 로그인 후 [ Springer BioChip Journal 열람하기 ] 버튼을 클릭하시면 새창으로 열립니다. |
